HELP! My 2 year old female indoor cat has been pooping outside of her litter box!

My 2 year old female indoor cat has been pooping outside of her litter box. My husband and I feel like we have tried everything. We took her to the vet, switched to a different litter, switched to a new box, changed the location, added another litter box, etc. You name it, we have probably tried it! Once we made the changes she used the box for about 3 weeks and then all of a sudden stopped. She only does it at night and it's always in the same spot on our bedroom rug. Now, I am 29 weeks pregnant and am due in December. We really need help figuring out what is going on before the baby comes. I can't have her pooping on the floor with a newborn! HELP!
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