My beloved 10-year old Persian started peeing/pooping on the laundry pile when we were on vacation at Xmas. It has escalated to more places around the house since then. Usually on carpeting, stairs, rugs, or anything left on the floor. (Obviously I try not to leave anything on the floor). She's been to the vet twice for this issue (no clear answers or issues found), has taken antibiotics to clear up possible infections, we clean her (5!) litter boxes 2x daily, I positioned more boxes around the house so there is always one nearby, we started introducing wet food, got her a new kitty bubbler, I'm giving her anti anxiety supplements and spraying calming kitty pheromones in frequently-used pooping places.... HELP! Next step is giving her up for adoption. I'm at my wit's end.